Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937642 | 0.98 | MAP3K12 (0.55) | MAP3K12TNF | |
| SCHEMBL19937787 | 0.95 | MAP3K12 (0.54) | MAP3K12TNF | |
| SCHEMBL19937632 | 0.82 | MAP3K12 (0.54) | MAP3K12 | |
| SCHEMBL19937757 | 0.81 | MAP3K12 (0.54) | MAP3K12 | |
| SCHEMBL19937762 | 0.81 | MAP3K12 (0.52) | MAP3K12 | |
| SCHEMBL19937624 | 0.80 | MAP3K12 (0.54) | MAP3K12 | |
| SCHEMBL19937663 | 0.80 | MAP3K12 (0.50) | MAP3K12 | |
| SCHEMBL19937789 | 0.79 | INSR (0.42) | MAP3K12 | |
| SCHEMBL19937610 | 0.79 | MAP3K12 (0.51) | MAP3K12 | |
| SCHEMBL19937634 | 0.78 | MAP3K11 (0.52) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945938-B1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2018-03-07 | — | — | EP | disclosed |