Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 6/20 | 0.38 |
| ▸ | NMT1 | P30419 | 6/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19939537 | 0.93 | NMT2 (0.44) | NMT2NMT1 | |
| SCHEMBL19897826 | 0.87 | KCNA5 (0.41) | KCNA5CHRNA7NMT2NMT1KCNJ5 | |
| SCHEMBL19911759 | 0.87 | KCNA5 (0.41) | KCNA5CHRNA7NMT2NMT1KCNJ5 | |
| SCHEMBL19939874 | 0.80 | SYK (0.40) | KCNA5 | |
| SCHEMBL19897871 | 0.80 | NMT2 (0.41) | NMT2NMT1 | |
| SCHEMBL19897870 | 0.80 | NMT2 (0.41) | NMT2NMT1 | |
| SCHEMBL19911752 | 0.78 | HTR1B (0.41) | — | |
| SCHEMBL29615262 | 0.78 | HTR1B (0.41) | — | |
| SCHEMBL19897836 | 0.76 | SCN8A (0.53) | NMT2NMT1 | |
| SCHEMBL30394859 | 0.76 | SCN8A (0.53) | NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507284-B1 | BIARYL COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2018044963-A1 | BIARYL COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-08 | — | — | WO | disclosed |