Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252920 | 0.79 | TSHR (0.44) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL4118673 | 0.78 | CYP3A4 (0.41) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL3251615 | 0.77 | TSHR (0.48) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL4116943 | 0.75 | SCN9A (0.37) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL6953710 | 0.75 | ALDH1A1 (0.42) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL31016250 | 0.74 | SMN1; SMN2 (0.42) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL9567857 | 0.74 | SMN1; SMN2 (0.42) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL31016248 | 0.74 | SMN1; SMN2 (0.42) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL4125270 | 0.73 | LPAR1 (0.38) | ALDH1A1TDP1KMT2AMAPTABL1 | |
| SCHEMBL3255465 | 0.72 | RECQL (0.46) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064717-A1 | DEUTERATED ANALONGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | GABA THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064717-A1 | DEUTERATED ANALONGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | CYP2D6, CYP2S1, CYP3A43 | CYP3A4 22/4885TSHR 4420/4885ALDH1A1 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.