Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922864 | 0.90 | GCGR (0.57) | GCGRSLC6A2P2RY14RXRARXRB | |
| SCHEMBL19922788 | 0.90 | GCGR (0.61) | GCGRSLC6A2P2RY14RXRARXRB | |
| SCHEMBL19922907 | 0.89 | GCGR (0.65) | GCGRSLC6A2P2RY14RXRARXRB | |
| SCHEMBL19922853 | 0.88 | GCGR (0.59) | GCGRSLC6A2P2RY14 | |
| SCHEMBL19922870 | 0.87 | GCGR (0.58) | GCGRSLC6A2P2RY14 | |
| SCHEMBL19922897 | 0.84 | GCGR (0.55) | GCGRSLC6A2P2RY14RXRARXRB | |
| SCHEMBL19970067 | 0.79 | GCGR (0.70) | GCGR | |
| SCHEMBL19922844 | 0.79 | GCGR (0.76) | GCGR | |
| SCHEMBL19922820 | 0.78 | GCGR (0.81) | GCGR | |
| SCHEMBL19922783 | 0.78 | GCGR (0.77) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064686-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064686-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | GPR119, GIPR, GLP1R | GCGR 4/4885SLC6A2 738/4885P2RY14 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.