Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 14/20 | 0.60 |
| ▸ | PROKR1 | Q8TCW9 | 14/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940790 | 0.91 | FPR2 (0.60) | FPR2PROKR1ALDH1A1RPS6KB1 | |
| SCHEMBL19941210 | 0.79 | FPR2 (0.59) | FPR2PROKR1LMNAKMT2A | |
| SCHEMBL19940816 | 0.78 | FPR2 (0.60) | FPR2PROKR1LMNA | |
| SCHEMBL19941260 | 0.77 | FPR2 (0.62) | FPR2PROKR1LMNAKMT2A | |
| SCHEMBL15549371 | 0.75 | FPR2 (1.00) | FPR2PROKR1LMNAKMT2A | |
| SCHEMBL19941050 | 0.75 | FPR2 (0.62) | FPR2PROKR1LMNAKMT2A | |
| SCHEMBL19941295 | 0.74 | FPR2 (0.63) | FPR2PROKR1ALDH1A1LMNAKMT2A | |
| SCHEMBL19941231 | 0.72 | FPR2 (0.60) | FPR2PROKR1 | |
| SCHEMBL19941190 | 0.71 | FPR2 (0.63) | FPR2PROKR1 | |
| SCHEMBL19941118 | 0.71 | FPR2 (0.63) | FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | disclosed |