Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 9/20 | 0.60 |
| ▸ | PROKR1 | Q8TCW9 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940734 | 0.91 | FPR2 (0.60) | FPR2PROKR1ALDH1A1RPS6KB1 | |
| SCHEMBL15549113 | 0.75 | FPR2 (1.00) | FPR2PROKR1 | |
| SCHEMBL2056158 | 0.74 | ALDH1A1 (0.61) | FPR2PROKR1ALDH1A1RPS6KB1SLC6A2 | |
| SCHEMBL19940809 | 0.73 | FPR2 (0.63) | FPR2PROKR1 | |
| SCHEMBL19941200 | 0.71 | FPR2 (0.59) | FPR2PROKR1 | |
| SCHEMBL15549371 | 0.71 | FPR2 (1.00) | FPR2PROKR1 | |
| SCHEMBL20349468 | 0.70 | ALDH1A1 (0.56) | FPR2PROKR1ALDH1A1RPS6KB1SLC6A2 | |
| SCHEMBL19941260 | 0.70 | FPR2 (0.62) | FPR2PROKR1TP53 | |
| SCHEMBL19941210 | 0.69 | FPR2 (0.59) | FPR2PROKR1 | |
| SCHEMBL22642448 | 0.68 | ALDH1A1 (0.61) | FPR2PROKR1ALDH1A1RPS6KB1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | disclosed |