Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 19/20 | 0.54 |
| ▸ | FPR2 | P25090 | 15/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940834 | 0.80 | PROKR1 (0.83) | PROKR1FPR2 | |
| SCHEMBL19940747 | 0.75 | PROKR1 (0.64) | PROKR1FPR2 | |
| SCHEMBL19941067 | 0.74 | FPR2 (0.61) | PROKR1FPR2 | |
| SCHEMBL19941061 | 0.73 | FPR2 (0.60) | PROKR1FPR2 | |
| SCHEMBL19941308 | 0.73 | FPR2 (0.62) | PROKR1FPR2 | |
| SCHEMBL15548712 | 0.70 | PROKR1 (1.00) | PROKR1FPR2 | |
| SCHEMBL19940766 | 0.69 | FPR2 (0.64) | PROKR1FPR2 | |
| SCHEMBL19941290 | 0.67 | FPR2 (0.65) | PROKR1FPR2 | |
| SCHEMBL19941211 | 0.63 | FPR2 (0.65) | PROKR1FPR2 | |
| SCHEMBL19941296 | 0.63 | FPR2 (0.62) | PROKR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | disclosed |