Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358416 | 0.92 | MPL (0.68) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL3346242 | 0.88 | CYP1A2 (0.73) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL29362512 | 0.87 | ALDH1A1 (0.72) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL29932227 | 0.87 | ALDH1A1 (0.72) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL92057 | 0.87 | ALDH1A1 (0.72) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL1161501 | 0.87 | ALDH1A1 (0.72) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL3184580 | 0.86 | ALDH1A1 (0.71) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL5786859 | 0.86 | ALDH1A1 (0.71) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL1435737 | 0.86 | ALDH1A1 (0.71) | MPLCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL1435734 | 0.86 | ALDH1A1 (0.71) | MPLCYP1A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065073-A1 | PROCESS FOR MAKING SOLID PARTICLES | THE PROCTER & GAMBLE COMPANY | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065073-A1 | PROCESS FOR MAKING SOLID PARTICLES | FUS, AUP1, NUP205 | MPL 3974/4885CYP1A2 4011/4885ALDH1A1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.