Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19941882 | 0.85 | ATM (0.48) | ATMAHCYCARM1DOT1LADORA1 | |
| SCHEMBL12740454 | 0.83 | ADORA3 (0.57) | AHCYDOT1LADORA1ADORA3EHMT1 | |
| SCHEMBL6900816 | 0.81 | ATM (0.76) | ATMAHCYCARM1DOT1LADORA1 | |
| SCHEMBL19941881 | 0.80 | AHCY (0.61) | AHCYCARM1DOT1LADORA1ADORA3 | |
| SCHEMBL9940469 | 0.79 | PI4KA (0.67) | ATMAHCYCARM1DOT1LADORA3 | |
| SCHEMBL9940477 | 0.79 | PI4KA (0.67) | ATMAHCYCARM1DOT1LADORA3 | |
| SCHEMBL15395696 | 0.79 | PI4KA (0.67) | ATMAHCYCARM1DOT1LADORA3 | |
| SCHEMBL14030736 | 0.78 | ADORA3 (0.59) | AHCYDOT1LADORA1ADORA3EHMT1 | |
| SCHEMBL13449217 | 0.78 | ADORA3 (0.59) | AHCYDOT1LADORA1ADORA3EHMT1 | |
| SCHEMBL13239706 | 0.76 | ADORA3 (0.66) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045204-A1 | CYCLIC DINUCLEOTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH STING (STIMULATOR OF INTERFERON GENES) ACTIVITY | IFM THERAPEUTICS, INC (US) | 2018-03-08 | — | — | WO | disclosed |