SCHEMBL19943

SCHEMBL19943

O=C=Nc1ccc(Cc2ccc(N=C=O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 1.00
TSHR P16473 3/20 1.00
CYP1A2 P05177 1/20 0.67
TDP1 Q9NUW8 3/20 0.45
MAPK1 P28482 2/20 0.45
P2RY6 Q15077 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
TRPA1 O75762 1/20 0.42
SLC22A2 O15244 1/20 0.38
ALDH1A1 P00352 4/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CYP2C9 P11712 2/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12852256 1.00 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL1396496 1.00 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL2044965 1.00 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TDP1MAPK1
Ammonia Solution, Strong SCHEMBL3504367 0.98 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL30634516 0.98 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TDP1MAPK1
Water SCHEMBL8522858 0.98 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TDP1MAPK1
Ethane SCHEMBL20537385 0.95 CYP3A4 (0.91) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL2988002 0.93 CYP3A4 (0.87) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL22966327 0.93 CYP3A4 (0.87) CYP3A4TSHRCYP1A2TDP1MAPK1
SCHEMBL6053390 0.93 CYP3A4 (0.87) CYP3A4TSHRCYP1A2TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 66475 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146217-A1 LAUNDRY CARE ADDITIVE PARTICLES THE PROCTER & GAMBLE COMPANY (US) 2026-05-28 US claimed
EP-4747293-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A TERMINAL DIALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP claimed
EP-4747294-A1 OPTICAL MATERIAL DERIVED FROM A POLYMERIZABLE COMPOSITION CONTAINING A HETERODIFUNCTIONAL ALKYNE COMPOUND Essilor International (FR) 2026-05-27 EP claimed
EP-4747311-A1 PERFLUOROPOLYETHER COPOLYMERS FOR BIOMEDICAL APPLICATIONS Axoft, Inc. (US) 2026-05-27 EP claimed
EP-4748867-A1 FOAMED WATERPROOFING COATING Saint-Gobain Weber France (FR) 2026-05-27 EP claimed
EP-4261345-B1 CONVEYOR BELT, IN PARTICULAR TRANSFER BELT FOR A PAPER MACHINE HEIMBACH GMBH (DE) 2026-05-27 EP claimed
EP-4748876-A1 DEPOLYMERIZATION OF POLYURETHANE AND POLYISOCYANURATE FOAMS USING AMINOLYSIS AND RELATED METHODS Vito NV (BE) 2026-05-27 EP claimed
EP-4747295-A1 OPTICAL MATERIAL DERIVED FROM A PREPOLYMER OBTAINED FROM A HETERODIFUNCTIONAL ALKYNE COMPOUND ESSILOR INTERNATIONAL (FR) 2026-05-27 EP claimed
CN-122080839-A PUR hot melt adhesive based on vinyl copolymerized elastomer modification and preparation method thereof 2026-05-26 CN claimed
CN-122080843-A Thermoplastic polyurethane resin for bonding water-repellent cloth and preparation method and application thereof 2026-05-26 CN claimed
US-3940542-A Polyurethane hydrogel fibers and tapes and composites with natural and other synthetic fibers or films UNION CARBIDE CORPORATION (US) 1976-02-24 US claimed
US-3939123-A HIGH WATER SWELLABILITY UNION CARBIDE CORPORATION (US) 1976-02-17 US claimed
US-3939105-A Microporous polyurethane hydrogels, method and composites with natural and other synthetic fibers or films UNION CARBIDE CORPORATION (US) 1976-02-17 US claimed
US-3937673-A DIELECTRICS PHELPS DODGE INDUSTRIES, INC. (US) 1976-02-10 US claimed
US-3935132-A POLYURETHANE UNION CARBIDE CORPORATION (US) 1976-01-27 US claimed
US-3933756-A Process of preparation of synthetic resins by reacting a cross-linked isocyanate polyaddition product with low molecular weight polyisocyanate followed by reaction with an amino alkyl silane BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed
US-3933759-A Heat-activatable, storage-stable polyurethane powders E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-01-20 US claimed
US-3933677-A Preparation of aqueous dispersions of blocked aromatic polyisocyanates E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-01-20 US claimed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US claimed
US-3931065-A POLYURETHANE-MODIFIED POLYISOCYANURATE FOAM AND A METHOD FOR THE PREPARATION THEREOF NISSHIN BOSEKI KABUSHIKI KAISHA (JA) 1976-01-06 US claimed