Ethane

Ethane

SCHEMBL20537385

CC.O=C=Nc1ccc(Cc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.91
TSHR P16473 3/20 0.91
CYP1A2 P05177 1/20 0.62
TRPA1 O75762 1/20 0.44
TDP1 Q9NUW8 3/20 0.42
MAPK1 P28482 2/20 0.42
P2RY6 Q15077 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KMT2A Q03164 1/20 0.37
SLC22A2 O15244 1/20 0.35
ALDH1A1 P00352 4/20 0.34
LMNA P02545 3/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044965 0.95 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL1396496 0.95 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL12852256 0.95 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL19943 0.95 CYP3A4 (1.00) CYP3A4TSHRCYP1A2TRPA1TDP1
Ammonia Solution, Strong SCHEMBL3504367 0.93 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TRPA1TDP1
Water SCHEMBL8522858 0.93 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL30634516 0.93 CYP3A4 (0.95) CYP3A4TSHRCYP1A2TRPA1TDP1
Alcohol SCHEMBL28205587 0.90 CYP3A4 (0.80) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL10304668 0.90 CYP3A4 (0.80) CYP3A4TSHRCYP1A2TRPA1TDP1
SCHEMBL2988002 0.89 CYP3A4 (0.87) CYP3A4TSHRCYP1A2TRPA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390019-A1 METHOD AND DEVICE FOR PRODUCING A FIBER-REINFORCED SEMI-FINISHED PLATE BY ULTRASONIC WELDING Covestro Deutschland AG (DE) 2018-10-24 EP disclosed