Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852256 | 1.00 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL1396496 | 1.00 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL19943 | 1.00 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL3504367 | 0.98 | CYP3A4 (0.95) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL30634516 | 0.98 | CYP3A4 (0.95) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| Water SCHEMBL8522858 | 0.98 | CYP3A4 (0.95) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| Ethane SCHEMBL20537385 | 0.95 | CYP3A4 (0.91) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL2988002 | 0.93 | CYP3A4 (0.87) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL22966327 | 0.93 | CYP3A4 (0.87) | CYP3A4TSHRCYP1A2TDP1MAPK1 | |
| SCHEMBL6053390 | 0.93 | CYP3A4 (0.87) | CYP3A4TSHRCYP1A2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350103-B2 | Spray foam splint | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2019-07-16 | — | — | US | disclosed |
| CN-109652993-A | Shape memory polyurethane composition and the laminate for using it | 台北科技大学 | 2019-04-19 | — | — | CN | disclosed |
| US-20160317343-A1 | SPRAY FOAM SPLINT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2016-11-03 | — | — | US | disclosed |
| US-9427489-B2 | Spray foam splint | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2016-08-30 | — | — | US | disclosed |
| US-20130324897-A1 | SPRAY FOAM SPLINT | USA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2013-12-05 | — | — | US | disclosed |
| EP-2516496-A2 | ONE-SHOT PROCESS FOR THE PRODUCTION OF THERMOPLASTIC POLYURETHANE MODIFIED WITH STYRENIC BLOCK COPOLYMERS | Epaflex Polyurethanes S.r.l. (IT) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012067620-A1 | SPRAY FOAM SPLINT | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF WILLIAM BEAUMONT ARMY (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011077234-A2 | ONE-SHOT PROCESS FOR THE PRODUCTION OF THERMOPLASTIC POLYURETHANE MODIFIED WITH STYRENIC BLOCK COPOLYMERS | EPAFLEX POLYURETHANES S.R.L. (IT) | 2011-06-30 | — | — | WO | disclosed |