Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | GRB2 | P62993 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590897 | 1.00 | F2 (0.32) | F2ACEPLGPLATGRB2 | |
| SCHEMBL20611442 | 0.90 | ACE (0.34) | ACECAPN1CTSB | |
| SCHEMBL20612266 | 0.86 | PLG (0.32) | F2ACEPLGPLATGRB2 | |
| SCHEMBL19943880 | 0.86 | PLG (0.32) | F2ACEPLGPLATGRB2 | |
| SCHEMBL20611525 | 0.84 | ACE (0.36) | ACECAPN1 | |
| SCHEMBL24590826 | 0.83 | PDE9A (0.30) | PLGPLAT | |
| SCHEMBL24590886 | 0.81 | ACE (0.35) | ACEPLGPLAT | |
| SCHEMBL20611651 | 0.78 | PLG (0.30) | ACEPLGPLAT | |
| SCHEMBL20611507 | 0.77 | PEPD (0.42) | F2PLGGRB2CAPN1 | |
| SCHEMBL19943549 | 0.76 | PDE9A (0.34) | CAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045313-A1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2018-03-08 | — | — | WO | disclosed |