Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590886 | 0.93 | ACE (0.35) | ACEPREP | |
| SCHEMBL20611442 | 0.88 | ACE (0.34) | ACECAPN1 | |
| SCHEMBL24590883 | 0.87 | ACE (0.40) | ACEPREP | |
| SCHEMBL24590855 | 0.85 | FKBP1A (0.37) | — | |
| SCHEMBL20611696 | 0.84 | FKBP1A (0.38) | — | |
| SCHEMBL24590897 | 0.84 | F2 (0.32) | ACECAPN1 | |
| SCHEMBL19943848 | 0.84 | F2 (0.32) | ACECAPN1 | |
| SCHEMBL24590869 | 0.82 | PREP (0.36) | PREPCAPN1 | |
| SCHEMBL20611422 | 0.79 | FKBP1A (0.33) | — | |
| SCHEMBL24590933 | 0.79 | FKBP1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265083-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3038640-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2019-01-02 | — | — | EP | disclosed |