Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611525 | 0.93 | ACE (0.36) | ACEPREP | |
| SCHEMBL20611442 | 0.85 | ACE (0.34) | ACE | |
| SCHEMBL20612095 | 0.85 | FKBP1A (0.35) | ACE | |
| SCHEMBL20612067 | 0.83 | PREP (0.34) | PREPPLGPLAT | |
| SCHEMBL24590897 | 0.81 | F2 (0.32) | ACEPLGPLAT | |
| SCHEMBL19943848 | 0.81 | F2 (0.32) | ACEPLGPLAT | |
| SCHEMBL24590877 | 0.81 | PLG (0.33) | ACEPLGPLAT | |
| SCHEMBL24590906 | 0.81 | PLG (0.33) | ACEPLGPLAT | |
| SCHEMBL24590883 | 0.80 | ACE (0.40) | ACEPREP | |
| SCHEMBL24590904 | 0.79 | PLG (0.37) | PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265083-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2022-07-06 | — | — | EP | disclosed |