⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944063 | 0.84 | — | — | |
| SCHEMBL19619212 | 0.82 | LRAT (0.30) | — | |
| SCHEMBL19944109 | 0.81 | — | — | |
| SCHEMBL19619250 | 0.80 | LRAT (0.36) | — | |
| SCHEMBL13873391 | 0.74 | — | — | |
| SCHEMBL13890114 | 0.74 | — | — | |
| SCHEMBL19619252 | 0.73 | — | — | |
| SCHEMBL19944540 | 0.71 | POLB (0.46) | — | |
| SCHEMBL19619219 | 0.71 | — | — | |
| SCHEMBL15828080 | 0.62 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064743-A1 | NOVEL AMINOGLYCOSIDES AND USES THEREOF IN THE TREATMENT OF GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-03-08 | — | — | US | disclosed |