Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944346 | 0.89 | THRB (0.48) | ACACBTHRBMAPTNPC1RAB9A | |
| SCHEMBL19944710 | 0.89 | THRB (0.48) | THRBHPGD | |
| SCHEMBL19944466 | 0.89 | CYP2C9 (0.53) | THRBMAPTKMT2AALDH1A1 | |
| SCHEMBL12607101 | 0.87 | THRB (0.41) | THRBMAPTPOLBLMNACYP1A2 | |
| SCHEMBL19944472 | 0.87 | THRB (0.64) | ACACBTHRBKMT2AMEN1LMNA | |
| SCHEMBL4759200 | 0.86 | KDM4E (0.40) | THRBMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL15385985 | 0.86 | THRB (0.48) | THRBMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL5088322 | 0.85 | THRB (0.57) | THRBMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL19624192 | 0.85 | KMT2A (0.48) | PARP10THRBMAPTNPC1POLB | |
| SCHEMBL19944445 | 0.84 | THRB (0.60) | THRBKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641831-B | Monomers, polymers, preparation method and use thereof | 东莞东阳光医疗智能器件研发有限公司 | 2021-09-10 | — | — | CN | disclosed |
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |