Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944362 | 0.89 | ACACB (0.46) | THRBACACBALDH1A1LMNAMAPT | |
| SCHEMBL19944472 | 0.89 | THRB (0.64) | THRBACACBALDH1A1LMNAKMT2A | |
| SCHEMBL19944445 | 0.86 | THRB (0.60) | THRBALDH1A1HPGDKMT2A | |
| SCHEMBL19944710 | 0.85 | THRB (0.48) | THRBHPGD | |
| SCHEMBL19944466 | 0.85 | CYP2C9 (0.53) | THRBMAOBALDH1A1MAPTKMT2A | |
| SCHEMBL13865592 | 0.84 | THRB (0.43) | THRBMAOBRXRARXRBMAPT | |
| SCHEMBL19944439 | 0.83 | ADRB2 (0.48) | THRBACACBALDH1A1LMNAKMT2A | |
| SCHEMBL19944469 | 0.83 | MAPK1 (0.48) | ALDH1A1GAA | |
| SCHEMBL12607101 | 0.83 | THRB (0.41) | THRBMAOBLMNAMAPT | |
| SCHEMBL19944471 | 0.83 | THRB (0.46) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641831-B | Monomers, polymers, preparation method and use thereof | 东莞东阳光医疗智能器件研发有限公司 | 2021-09-10 | — | — | CN | disclosed |
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |