Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 12/20 | 0.72 |
| ▸ | CASP1 | P29466 | 5/20 | 0.54 |
| ▸ | CASP7 | P55210 | 4/20 | 0.54 |
| ▸ | CASP9 | P55211 | 3/20 | 0.54 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944652 | 0.88 | CASP3 (0.64) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL20356163 | 0.85 | CASP3 (0.72) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL20052403 | 0.85 | CASP3 (0.72) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL15462619 | 0.85 | CASP3 (0.72) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19944916 | 0.82 | CASP3 (0.49) | CASP3PTPN1TLR2 | |
| SCHEMBL20356102 | 0.82 | CASP3 (0.63) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL15462726 | 0.82 | CASP3 (0.63) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL18471954 | 0.81 | CASP3 (0.69) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL30429101 | 0.81 | KMT2A (0.56) | CASP3PTPN1TLR2 | |
| SCHEMBL19944934 | 0.80 | CASP3 (0.60) | CASP3CASP1CASP7CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |