SCHEMBL1994481

SCHEMBL1994481

CCO[Si](C)(C)CCCN=Cc1ccc(N(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
KDM4E B2RXH2 8/20 0.40
MAPT P10636 6/20 0.40
KMT2A Q03164 5/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
MEN1 O00255 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MAPK1 P28482 2/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 4/20 0.39
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996638 0.89 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL329225 0.89 ALDH1A1 (0.43) ALDH1A1CA12CA1CA2CA9
SCHEMBL3839964 0.86 ALDH1A1 (0.44) ALDH1A1CA12CA1CA2CA9
SCHEMBL26370522 0.86 ALDH1A1 (0.39) ALDH1A1CA2KDM4EKMT2AMEN1
SCHEMBL1998837 0.85 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL26370525 0.85 ALDH1A1 (0.39) ALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL26370539 0.83 CA2 (0.40) ALDH1A1CA12CA1CA2CA9
SCHEMBL8096797 0.83 CA2 (0.40) ALDH1A1CA12CA1CA2CA9
SCHEMBL29331568 0.82 ALDH1A1 (0.36) ALDH1A1CA12CA1CA2CA9
SCHEMBL3840919 0.81 ALDH1A1 (0.44) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
US-20140134445-A1 POLYMERIC CONTACT MEDIA Yaeger, Evelyn (US) 2014-05-15 US disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20130244046-A1 POLYMERIC CONTACT MEDIA YAEGER, EVELYN 2013-09-19 US disclosed
US-8410215-B2 Thermoplastic resin composition and molded article obtained from the same JSR CORPORATION (JP) 2013-04-02 US disclosed
EP-2055737-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OBTAINED FROM THE SAME JSR CORP (JP) 2012-08-08 EP disclosed
EP-1245585-B1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORP (JP) 2008-05-21 EP disclosed
EP-1777263-A1 RESIN COMPOSITION AND MOLDED PRODUCT THEREOF JSR Corporation (JP) 2007-04-25 EP disclosed
EP-1600479-A1 Resin composition and golf ball JSR Corporation (JP) 2005-11-30 EP disclosed
EP-1293535-B1 Resin composition and golf ball JSR CORP (JP) 2005-08-03 EP disclosed
US-6887929-B2 Resin composition and golf ball JSR CORPORATION (JP) 2005-05-03 US disclosed
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030130425-A1 Resin composition and golf ball JSR CORPORATION (JP) 2003-07-10 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1293535-A2 Resin composition and golf ball JSR Corporation (JP) 2003-03-19 EP disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed