Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262966 | 0.79 | MCHR1 (0.34) | MCHR1GAAIDH1HRH1 | |
| SCHEMBL17263328 | 0.76 | CCR4 (0.40) | MCHR1IDH1HRH1 | |
| SCHEMBL12607354 | 0.75 | IDH1 (0.33) | MCHR1IDH1 | |
| SCHEMBL127293 | 0.75 | IDH1 (0.33) | MCHR1IDH1 | |
| SCHEMBL1999685 | 0.75 | SRC (0.35) | MCHR1IDH1 | |
| SCHEMBL5437866 | 0.75 | IDH1 (0.36) | MCHR1IDH1 | |
| SCHEMBL1569158 | 0.75 | IDH1 (0.33) | MCHR1ALDH1A1IDH1 | |
| SCHEMBL9045575 | 0.75 | GFER (0.42) | MCHR1GAAKMT2AALDH1A1IDH1 | |
| SCHEMBL5329328 | 0.75 | IDH1 (0.33) | MCHR1IDH1 | |
| SCHEMBL1912967 | 0.74 | IDH1 (0.33) | MCHR1IDH1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338885-B1 | Insecticidal N-Substituted (2-Substituted-1,3-Thiazol) Alkyl Sulfoximines | DOW AGROSCIENCES LLC (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2057135-B1 | INSECTICIDAL N-SUBSTITUTED (2- SUBSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| US-8183270-B2 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES, LLC (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183270-B2 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES, LLC (US) | 2012-05-22 | — | — | US | disclosed |
| EP-2338885-A1 | Insecticidal N-Substituted (2-Substituted-1,3-Thiazol) Alkyl Sulfoximines | Dow AgroSciences LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2338883-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol) alkyl sulfoximines | Dow AgroSciences LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2338884-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol) alkyl sulfoximines | Dow AgroSciences LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2338884-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol) alkyl sulfoximines | Dow AgroSciences LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20110060018-A1 | INSECTICIDAL N-SUBSTITUTED (2-SUBSTITUTED-1,3-THIAZOL)ALKYL SULFOXIMINES | CORTEVA AGRISCIENCE LLC | 2011-03-10 | — | — | US | disclosed |
| US-20110060018-A1 | INSECTICIDAL N-SUBSTITUTED (2-SUBSTITUTED-1,3-THIAZOL)ALKYL SULFOXIMINES | CORTEVA AGRISCIENCE LLC | 2011-03-10 | — | — | US | disclosed |
| US-7863303-B2 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2011-01-04 | — | — | US | disclosed |
| US-7863303-B2 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2011-01-04 | — | — | US | disclosed |
| US-7863303-B2 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2011-01-04 | — | — | US | disclosed |
| EP-2057135-A1 | INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES | Dow AgroSciences LLC (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008027539-A1 | INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20080058394-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058394-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058394-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058394-A1 | Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines | TST, NIT2, MSL1 | MCHR1 2202/4885GAA 4482/4885MEN1 2936/4885 |
| US-20110060018-A1 | INSECTICIDAL N-SUBSTITUTED (2-SUBSTITUTED-1,3-THIAZOL)ALKYL SULFOXIMINES | TST, NIT2, MSL1 | MCHR1 2202/4885GAA 4482/4885MEN1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.