Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 15/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114750 | 0.85 | PDE2A (0.51) | PDE2AEPHX2SLC7A5 | |
| SCHEMBL17797443 | 0.85 | PDE2A (0.51) | PDE2AEPHX2SLC7A5 | |
| SCHEMBL19946332 | 0.80 | PDE2A (0.53) | PDE2AEPHX2SLC7A5TRPM8 | |
| SCHEMBL16564005 | 0.78 | PDE2A (0.49) | PDE2AEPHX2TRPM8 | |
| SCHEMBL19946338 | 0.77 | PDE2A (0.64) | PDE2AEPHX2TRPM8 | |
| SCHEMBL19946334 | 0.77 | PDE2A (0.50) | PDE2AEPHX2SLC7A5TRPM8 | |
| SCHEMBL16563926 | 0.75 | PDE2A (0.57) | PDE2AEPHX2SLC7A5TRPM8 | |
| SCHEMBL16633121 | 0.74 | PDE2A (0.50) | PDE2AEPHX2SLC7A5TRPM8 | |
| SCHEMBL27828658 | 0.72 | PDE2A (0.48) | PDE2AEPHX2SLC7A5 | |
| SCHEMBL16563578 | 0.72 | PDE2A (0.61) | PDE2AEPHX2SLC7A5TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |
| CN-104245698-B | Nitrogen-containing heterocyclic compound | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-11-30 | — | — | CN | disclosed |