Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 18/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19946332 | 0.80 | PDE2A (0.53) | PDE2AEPHX2TRPM8 | |
| SCHEMBL19946345 | 0.80 | EPHX1 (0.42) | PDE2AEPHX2 | |
| SCHEMBL18249304 | 0.78 | PDE2A (1.00) | PDE2AEPHX2TRPM8 | |
| SCHEMBL20266802 | 0.78 | PDE2A (1.00) | PDE2AEPHX2TRPM8 | |
| SCHEMBL17797443 | 0.78 | PDE2A (0.51) | PDE2AEPHX2 | |
| SCHEMBL28114750 | 0.78 | PDE2A (0.51) | PDE2AEPHX2 | |
| SCHEMBL19946337 | 0.77 | PDE2A (0.50) | PDE2AEPHX2TRPM8 | |
| SCHEMBL19946334 | 0.77 | PDE2A (0.50) | PDE2AEPHX2TRPM8 | |
| Hydrochloric Acid SCHEMBL16563563 | 0.77 | PDE2A (0.97) | PDE2AEPHX2TRPM8 | |
| Hydrochloric Acid SCHEMBL17781163 | 0.77 | PDE2A (0.97) | PDE2AEPHX2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |