Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985789 | 0.80 | EPHX1 (0.46) | EPHX1EPHX2ALDH1A1MAPTGAA | |
| SCHEMBL19946334 | 0.80 | PDE2A (0.50) | EPHX2PDE2A | |
| SCHEMBL28433174 | 0.79 | EPHX1 (0.46) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL28519919 | 0.77 | EPHX1 (0.51) | EPHX1EPHX2ALDH1A1MAPTGAA | |
| SCHEMBL287345 | 0.76 | SMN1; SMN2 (0.44) | EPHX1ALDH1A1TDP1NPSR1TSHR | |
| SCHEMBL27974375 | 0.75 | EPHX2 (0.41) | EPHX1EPHX2ALDH1A1GAAKMT2A | |
| SCHEMBL27985769 | 0.75 | EPHX1 (0.44) | EPHX1EPHX2ALDH1A1SCN10AHRH3 | |
| SCHEMBL27985768 | 0.75 | EPHX1 (0.44) | EPHX1EPHX2ALDH1A1SCN10AHRH3 | |
| SCHEMBL954057 | 0.74 | EPHX1 (0.49) | EPHX1EPHX2ALDH1A1MAPTGAA | |
| SCHEMBL19946345 | 0.73 | EPHX1 (0.42) | EPHX1EPHX2ALDH1A1PDE2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |