Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978225 | 0.86 | SRC (0.41) | SMN1; SMN2NPSR1CYP2D6CYP1A2PKM | |
| SCHEMBL5932426 | 0.83 | TSHR (0.45) | SMN1; SMN2NPSR1CYP2D6TSHRTRPA1 | |
| SCHEMBL2835326 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2NPSR1CYP2D6TSHRTRPA1 | |
| Carfimate SCHEMBL1648782 | 0.81 | CYP2D6 (0.44) | SMN1; SMN2NPSR1CYP2D6CYP1A2PKM | |
| SCHEMBL5932510 | 0.81 | TSHR (0.44) | SMN1; SMN2NPSR1CYP2D6TSHRTRPA1 | |
| SCHEMBL7699172 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2NPSR1CYP2D6TSHRTRPA1 | |
| SCHEMBL15453000 | 0.81 | TSHR (0.44) | SMN1; SMN2NPSR1CYP2D6TSHRTRPA1 | |
| SCHEMBL28174202 | 0.81 | CTSD (0.44) | SMN1; SMN2NPSR1CYP2D6CYP1A2PKM | |
| SCHEMBL4801484 | 0.80 | TSHR (0.42) | SMN1; SMN2NPSR1CYP2D6CYP1A2PKM | |
| SCHEMBL8964823 | 0.80 | TSHR (0.52) | SMN1; SMN2NPSR1CYP2D6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| US-12486289-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-12377037-B2 | Cleavable comonomer strategy for accelerating removal of gel nail polish | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-08-05 | — | — | US | disclosed |
| WO-2025151874-A1 | INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-07-17 | — | — | WO | disclosed |
| US-20250144227-A1 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-05-08 | — | — | US | disclosed |
| US-20240423894-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-12-26 | — | — | US | disclosed |
| US-12116364-B2 | Heteroaryl compounds and uses thereof | APRINOIA THERAPEUTICS INC. (CN) | 2024-10-15 | — | — | US | disclosed |
| US-12083186-B2 | Methods for assembling scavenging particles | NANOTICS, LLC (US) | 2024-09-10 | — | — | US | disclosed |
| US-20240269319-A1 | METHODS FOR ASSEMBLING SCAVENGING PARTICLES | NANOTICS, LLC | 2024-08-15 | — | — | US | disclosed |
| US-20240228475-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE | CELGENE CORPORATION | 2024-07-11 | — | — | US | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| EP-1863800-A2 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007008226-A9 | PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS | HARVARD COLLEGE (US) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007056188-A1 | SYNTHESIS OF INHIBITORS OF FTSZ | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-05-18 | — | — | WO | disclosed |
| EP-1753713-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2007013965-A2 | SYNTHESIS OF SCABRONINES AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2007-02-01 | — | — | WO | disclosed |
| WO-2006102097-A2 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2005112945-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-12-01 | — | — | WO | disclosed |
| CN-1079679-C | Cascade polymer complexes, method for the production thereof and pharmaceutical agents containing said complexes | SCHERING AG (DE) | 2002-02-27 | — | — | CN | disclosed |
| CN-1189779-A | Cascade polymer complexes, method for the production thereof and pharmaceutical agents containing said complexes | SCHERING AG (DE) | 1998-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12377037-B2 | Cleavable comonomer strategy for accelerating removal of gel nail polish | PRKDC, POLR1C, PIK3C3 | SMN1; SMN2 4325/4885NPSR1 4275/4885CYP2D6 1514/4885 |
| US-20240423894-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | PRKDC, POLR1C, NACA | SMN1; SMN2 4034/4885NPSR1 4117/4885CYP2D6 1994/4885 |
| US-20250144227-A1 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | UGT2B17, ABCB4, IL17A | SMN1; SMN2 3215/4885NPSR1 3722/4885CYP2D6 208/4885 |
| US-12486289-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | GSK3A, GSK3B, PYGB | SMN1; SMN2 1825/4885NPSR1 3905/4885CYP2D6 673/4885 |
| US-20240228475-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE | AQP1, AQP3, ADH1C | SMN1; SMN2 738/4885NPSR1 1614/4885CYP2D6 134/4885 |
| US-12116364-B2 | Heteroaryl compounds and uses thereof | MAPT, APP, SLCO1B3 | SMN1; SMN2 2412/4885NPSR1 806/4885CYP2D6 365/4885 |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | SOST, SIK2, SIK1 | SMN1; SMN2 3838/4885NPSR1 865/4885CYP2D6 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.