Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPM2A | O95278 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435837 | 0.83 | NPC1 (0.46) | EPHX1ACACBMMP2MMP9MMP13 | |
| SCHEMBL28432279 | 0.80 | VCP (0.44) | ALOX5FFAR1MMP2MMP13ALDH1A1 | |
| SCHEMBL19946341 | 0.79 | EPHX1 (0.43) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL28430974 | 0.78 | UTS2R (0.41) | EPHX1ALOX5FFAR1MMP9 | |
| SCHEMBL28431008 | 0.75 | LMNA (0.43) | FFAR1MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL27985789 | 0.74 | EPHX1 (0.46) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL28436046 | 0.72 | ALOX5 (0.48) | ALOX5FFAR1TRPM8ALDH1A1 | |
| SCHEMBL28354626 | 0.72 | TSHR (0.49) | ALDH1A1 | |
| SCHEMBL28519919 | 0.71 | EPHX1 (0.51) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL403812 | 0.71 | APP (0.50) | EPHX2ACACBFFAR1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484462-A | 4-isoxazoline compound and preparation method thereof | 南京工业大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111484462-A | 4-isoxazoline compound and preparation method thereof | 南京工业大学 | 2020-08-04 | — | — | CN | disclosed |