Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19946345 | 0.82 | EPHX1 (0.42) | PDE2AAKR1C2 | |
| SCHEMBL29142736 | 0.79 | UTS2R (0.43) | KIF11CES2CES1UTS2RFFAR1 | |
| SCHEMBL2364380 | 0.79 | KIF11 (0.47) | KIF11CES2CES1PDE2AGSK3B | |
| SCHEMBL19946338 | 0.74 | PDE2A (0.64) | PDE2A | |
| SCHEMBL28364043 | 0.73 | KIF11 (0.42) | KIF11CES2CES1PDE2AAKR1C3 | |
| SCHEMBL28364047 | 0.73 | KIF11 (0.42) | KIF11CES2CES1PDE2AAKR1C3 | |
| SCHEMBL19517122 | 0.71 | KCNN4 (0.39) | — | |
| SCHEMBL20266626 | 0.71 | PDE2A (0.49) | KIF11CES2CES1PDE2AACP3 | |
| SCHEMBL18255589 | 0.71 | PDE2A (0.49) | KIF11CES2CES1PDE2AACP3 | |
| SCHEMBL5026454 | 0.70 | PARP10 (0.34) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |