Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | THRB | P10828 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metronidazole SCHEMBL2221140 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL5313560 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL31108924 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL9455119 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL23042 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL9481347 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL9482744 | 0.91 | LMNA (1.00) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL5885668 | 0.90 | LMNA (0.97) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL40922 | 0.90 | LMNA (0.97) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL20587361 | 0.90 | LMNA (0.97) | LMNAMAPK1ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072962-A1 | LUBRICATING OIL COMPOSITION | JXTG NIPPON OIL & ENERGY CORPORATION (JP) | 2018-03-15 | — | — | US | disclosed |