Metronidazole

Metronidazole

SCHEMBL23042

Cc1ncc([N+](=O)[O-])n1CCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
ALDH1A1 P00352 3/20 1.00
MAPK1 P28482 2/20 1.00
THRB P10828 1/20 1.00
TSHR P16473 1/20 1.00
CA1 P00915 5/20 0.64
CA2 P00918 5/20 0.64
CA9 Q16790 5/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
GLA P06280 1/20 0.63
ATM Q13315 1/20 0.63
CA12 O43570 4/20 0.59
CHRM1 P11229 1/20 0.58
GAA P10253 1/20 0.56
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.53
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metronidazole SCHEMBL9481347 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL9455119 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL31108924 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL9482744 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL2221140 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL5313560 1.00 LMNA (1.00) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL5595814 0.98 LMNA (0.97) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL8675069 0.98 LMNA (0.97) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL3453244 0.98 LMNA (0.97) LMNAALDH1A1MAPK1THRBTSHR
Metronidazole SCHEMBL21295019 0.98 LMNA (0.97) LMNAALDH1A1MAPK1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 156762 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4749288-A1 COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM COSA Group GmbH (DE) 2026-05-27 EP claimed
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
CN-122075587-A Traditional Chinese medicine composition for treating rose acne as well as preparation method and application thereof 2026-05-26 CN claimed
CN-122075397-A In-situ foam gel containing exosomes and preparation method and application thereof 2026-05-26 CN claimed
US-12636276-B1 Methods and compositions for treating hemorrhoids Wang, Jianmin (US) 2026-05-26 US claimed
CN-121754734-B Silk fibroin-based bionic artificial tympanic membrane with gradient structure and preparation method thereof Fuxiang Sitai medical technology (Suzhou) Co.,Ltd. (CN) 2026-05-26 CN claimed
WO-2026107208-A1 COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS THE METHODIST HOSPITAL (US) 2026-05-21 WO claimed
WO-2026106917-A1 EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL BioPhysics Pharma, Inc. (US) 2026-05-21 WO claimed
EP-4007582-B1 ANTIBIOTICS IN COMBINATION WITH PHOTODYNAMIC THERAPY FOR USE IN A METHOD OF ENHANCING THE ANTIMICROBIAL ACTION OF SYSTEMICALLY ADMINISTERED ANTIBIOTICS KOITE HEALTH OY (FI) 2026-05-20 EP claimed
CN-122056853-A Antibacterial agent based on graphite phase carbon nitride, and preparation method and application thereof 海南医科大学(海南省医学科学院) 2026-05-19 CN claimed
WO-1979000162-A1 GLASS-PLASTIC LAMINATE AND METHOD AND DEVICE FOR ITS PRODUCTION KEMANOBEL AB (SE) 1979-04-05 WO claimed
US-4136383-A MICROPROGRAMMED, MULTIPURPOSE PROCESSOR HAVING CONTROLLABLE EXECUTION SPEED NIPPON TELEGRAPH AND TELEPHONE PUBLIC CORPORATION (JP) 1979-01-23 US claimed
US-4102998-A INTRAUTERINE DEVICE WHICH RELEASES MEDICATION GUTNICK MORTON 1978-07-25 US claimed
US-4073928-A Therapeutic treatment for viral regional ileitis infection MERCER JAMES B 1978-02-14 US claimed
US-4053593-A PREVENTING AND CURING DISEASES IN FISH FRUMOFF LEW 1977-10-11 US claimed
US-4053580-A POLYSILOXANE, POLYOXYETHYLENE GLYCOL G. D. SEARLE & CO. (US) 1977-10-11 US claimed
US-4032645-A FOR SYSTEMIC TREATMENT OF ANAEROBIC INFECTIONS G. D. SEARLE & CO. (US) 1977-06-28 US claimed
US-4005356-A Ignition wave analyzer interface SUN ELECTRIC CORPORATION (US) 1977-01-25 US claimed
US-3952103-A Herpes viral infection treatment MERCER JAMES B 1976-04-20 US claimed
US-3946106-A POLYSILOXANES G. D. SEARLE & CO. (US) 1976-03-23 US claimed