SCHEMBL1995090

SCHEMBL1995090

CCO[SiH](OCC)C(C)CCOCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124765 0.91 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL767111 0.83 TSHR (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL232026 0.80 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1564440 0.79 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL19125484 0.77 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9580247 0.75 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1
SCHEMBL1843156 0.75 TSHR (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3394967 0.75 TSHR (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL230072 0.74 TSHR (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4924944 0.74 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP claimed
US-20110189486-A1 GLASS LAMINATE STRUCTURES AND METHODS OF MAKING SAME WENDELL JR JAY MORELL 2011-08-04 US claimed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
US-20220144974-A1 Modified High-Cis Polybutadiene Polymer, Related Methods And Rubber Compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-05-12 US disclosed
US-10259928-B2 Silane group-containing polymer composition and coatings containing same OMNOVA SOLUTIONS INC. (US) 2019-04-16 US disclosed
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed
US-6337370-B1 RADIATION TRANSPARENT POLYVINYL ALCOHOL POLYMER FOR PAINTS AND PROTECTIVE COATINGS KOREAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB SMN1; SMN2 1739/4885ALDH1A1 778/4885TDP1 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.