SCHEMBL767111

SCHEMBL767111

CO[SiH](OC)C(C)CCOCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230072 0.90 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10822315 0.89 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1995090 0.83 SMN1; SMN2 (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28550915 0.83 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8460322 0.82 ALDH1A1 (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28583354 0.81 TSHR (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7688097 0.80 SMN1; SMN2 (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3394967 0.77 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1843156 0.77 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15569798 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP claimed
CN-115746616-A Surface-modified hollow silica particles and surface-modified hollow silica dispersion 凯斯科技股份有限公司 2023-03-07 CN claimed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
US-20240228306-A9 DISPERSION OF EXFOLIATED PARTICLES OF LAYERED POLYSILICATE COMPOUND, AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2024-07-11 US disclosed
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
US-20240201593-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
EP-0437902-A1 Anti-fogging film TORAY INDUSTRIES, INC. (JP) 1991-07-24 EP disclosed
US-4950707-A PREVIOUSLY MODIFIED BY A DIMERCAPTO COMPOUND; ADHESIVES; SEALS; HEAT AND WEATHER RESISTANT; NONTACKY TOSHIBA SILICONE CO., LTD. (JP) 1990-08-21 US disclosed
US-4847357-A WEATHERPROOFING, HEAT RESISTANT SEALS TOSHIBA SILICONE CO., LTD. (JP) 1989-07-11 US disclosed
US-RE32272-E EPOXY GROUP-CONTAINING SILANE COMPOUND, POLYHDRIC ALCOHOL, POLYMER AND CURING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-28 US disclosed
US-4594379-A Containing an organosilicon compound in photoinitiator blend NIPPON SHEET GLASS CO., LTD. (JP) 1986-06-10 US disclosed
US-4522966-A CURABLE MIXTURE OF GLYCIDYL-CONTAINING ACRYLIC POLYMER, A POLYOXYALKYLENE GLYCOL AND CATALYST NIPPON SHEET GLASS CO., LTD. (JP) 1985-06-11 US disclosed
US-4439239-A Pigmented coating composition containing a mixture of alkoxysilanes PPG INDUSTRIES, INC. (US) 1984-03-27 US disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed
US-4394177-A Coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB TSHR 1694/4885SMN1; SMN2 1739/4885ALDH1A1 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.