Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 14/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997460 | 0.87 | HTR6 (0.41) | HTR6DRD2DRD3HTR1AHTR2A | |
| Trifluoroacetic Acid SCHEMBL1995099 | 0.78 | HTR6 (0.39) | NR1H3HTR6DRD2HTR1AHTR2A | |
| SCHEMBL1996220 | 0.76 | NR1H3 (0.35) | NR1H3HTR6PKMPKLR | |
| SCHEMBL1997578 | 0.76 | HTR6 (0.40) | HTR6DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1997494 | 0.76 | HTR6 (0.42) | HTR6DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1996895 | 0.74 | HTR6 (0.41) | HTR6DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1997771 | 0.73 | HTR6 (0.44) | HTR6DRD2HTR1AHTR2APKM | |
| Trifluoroacetic Acid SCHEMBL1996241 | 0.73 | HTR6 (0.43) | HTR6DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1996430 | 0.72 | HTR6 (0.41) | HTR6DRD2DRD3HTR1AHTR2A | |
| Trifluoroacetic Acid SCHEMBL4410635 | 0.67 | HTR6 (0.42) | HTR6DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960374-B2 | e.g. 2,5-methylene-9-(phenylsulfonyl)-1,2,3,4,5,9-hexahydro[1,5]oxazocino[3,2-e]indole; serotonin receptors antagonist or partial agonist; metabolic diseases, e.g. obesity, insulin resisitance, type 2 diabetes, eating disorders; antidepressant, anxiolytic agent; cosmetics | PROXIMAGEN LIMITED (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20080176829-A1 | Compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176829-A1 | Compounds | HTR6, HTR1B, HTR1A | NR1H3 201/4885HTR6 1/4885ACHE 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.