Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953091 | 0.91 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL19953052 | 0.86 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL1074104 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL19953173 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL19953164 | 0.83 | CYP11B2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL1076492 | 0.82 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL1073380 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL19953044 | 0.77 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL19953042 | 0.77 | PTGS2 (0.43) | PTGS2 | |
| SCHEMBL19967294 | 0.75 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048969-A1 | MULTI-TARGETED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-03-15 | — | — | WO | disclosed |