Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 4/20 | 0.46 |
| ▸ | CDC25B | P30305 | 4/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 4/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649364 | 0.78 | MALT1 (0.58) | CYP19A1MEN1KMT2APKMMAPK1 | |
| SCHEMBL8615961 | 0.77 | CDC25B (0.54) | CYP19A1PTPN1BACE1CDC25ACDC25B | |
| SCHEMBL6535771 | 0.75 | CDC25A (0.56) | CYP19A1PTPN1BACE1CDC25ACDC25B | |
| SCHEMBL7912021 | 0.74 | PTPN1 (0.52) | CYP19A1PTPN1BACE1CDC25ACDC25B | |
| SCHEMBL413750 | 0.74 | CYP19A1 (0.63) | CYP19A1PTPN1CDC25ACDC25BMAP2K7 | |
| SCHEMBL5810776 | 0.74 | PARK7 (0.58) | PTPN1BACE1CDC25ACDC25BTDP2 | |
| SCHEMBL9588537 | 0.73 | PTPN1 (0.76) | PTPN1BACE1CDC25ACDC25BMAP2K7 | |
| SCHEMBL30692083 | 0.72 | CDC25A (0.54) | CYP19A1PTPN1BACE1CDC25ACDC25B | |
| SCHEMBL21878874 | 0.72 | CDC25A (0.54) | CYP19A1PTPN1BACE1CDC25ACDC25B | |
| SCHEMBL11412192 | 0.72 | CYP19A1 (0.56) | CYP19A1PTPN1CDC25ACDC25BMAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |