Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.31 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18423334 | 0.81 | PDE4B (0.40) | EHMT2 | |
| SCHEMBL29613148 | 0.81 | PDE4B (0.40) | EHMT2 | |
| SCHEMBL19953409 | 0.80 | CYP2B6 (0.35) | FPR2CYP2B6TENT4ATENT4B | |
| SCHEMBL29613292 | 0.78 | CYP2C9 (0.36) | — | |
| SCHEMBL19252796 | 0.78 | CYP2C9 (0.36) | — | |
| SCHEMBL20888030 | 0.76 | KDM1A (0.35) | — | |
| SCHEMBL19953235 | 0.75 | CYP2B6 (0.33) | FPR2CYP2B6TENT4ATENT4B | |
| SCHEMBL19252797 | 0.75 | EHMT2 (0.38) | EHMT2 | |
| SCHEMBL20485497 | 0.70 | REN (0.35) | — | |
| SCHEMBL20485500 | 0.70 | REN (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047109-A1 | POLYCYCLIC PYRIDONE COMPOUNDS AS ANTIVIRALS | NOVARTIS AG (CH) | 2018-03-15 | — | — | WO | disclosed |