Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18423334 | 1.00 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19252797 | 0.93 | EHMT2 (0.38) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19252796 | 0.87 | CYP2C9 (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2C | |
| SCHEMBL29613292 | 0.87 | CYP2C9 (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2C | |
| SCHEMBL19273110 | 0.81 | KDM1A (0.42) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL28767997 | 0.81 | PDE4A (0.42) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL18423921 | 0.81 | PDE4A (0.50) | PDE4BPDE4APDE4CPDE4DKDM1A | |
| SCHEMBL19953407 | 0.81 | FPR2 (0.32) | EHMT2 | |
| SCHEMBL18424750 | 0.80 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL29613166 | 0.80 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831942-B | Fused indazolopyridinone compounds as antiviral agents | 诺华股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109071447-B | Tetracyclic pyridinone compounds as antiviral agents | 诺华股份有限公司 | 2022-04-22 | — | — | CN | disclosed |