Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263225 | 0.94 | KDM1A (0.60) | KDM1AMAOAMAOBTACR1TACR3 | |
| SCHEMBL13797297 | 0.81 | MCHR1 (0.56) | KDM1AMAOAMAOB | |
| SCHEMBL30447198 | 0.81 | MAP4K4 (0.47) | KDM1AMAOAMAOBGRIN2B | |
| SCHEMBL6866273 | 0.79 | NSD2 (0.62) | KDM1AMAOAMAOBCYP1A2MEN1 | |
| SCHEMBL6866279 | 0.79 | NSD2 (0.62) | KDM1AMAOAMAOBCYP1A2MEN1 | |
| SCHEMBL4040793 | 0.79 | ACHE (0.52) | MEN1KMT2AFAAHROCK2 | |
| SCHEMBL3364282 | 0.79 | KDM1A (0.60) | KDM1AMAOAMAOBTACR1TACR3 | |
| SCHEMBL22779486 | 0.78 | KDM1A (0.51) | KDM1AMAOAMAOBCYP1A2RAB9A | |
| SCHEMBL2755986 | 0.77 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL239554 | 0.77 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3509627-A1 | LYSINE SPECIFIC HISTONE DEMETHYLASE-1 INHIBITORS AND USES THEREFOR | University of Canberra (AU) | 2019-07-17 | — | — | EP | disclosed |
| WO-2018045422-A1 | LYSINE SPECIFIC HISTONE DEMETHYLASE-1 INHIBITORS AND USES THEREFOR | UNIVERSITY OF CANBERRA (AU) | 2018-03-15 | — | — | WO | disclosed |