SCHEMBL19953995

SCHEMBL19953995

Cc1cn(C2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CC(CN)O2)c(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.44
RNASE1 P07998 1/20 0.43
TK2 O00142 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19660825 0.91 TK1 (0.45) TK1RNASE1TK2
SCHEMBL409820 0.90 RNASE1 (0.50) TK1RNASE1TK2
SCHEMBL441127 0.90 RNASE1 (0.50) TK1RNASE1TK2
SCHEMBL27157713 0.87 TYMP (0.48) TK1RNASE1TK2
SCHEMBL9978645 0.86 TK1 (0.44) TK1RNASE1TK2
SCHEMBL14968223 0.86 TK1 (0.44) TK1RNASE1TK2
SCHEMBL9978644 0.85 TK1 (0.43) TK1RNASE1TK2
SCHEMBL14968221 0.85 TK1 (0.43) TK1RNASE1TK2
SCHEMBL14967959 0.84 TK1 (0.41) TK1RNASE1TK2
SCHEMBL23713976 0.84 TK1 (0.44) TK1RNASE1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9914745-B2 Morpholino-based antisense agent INDIAN ASSOCIATION FOR THE CULTIVATION OF SCIENCE (IN) 2018-03-13 US disclosed
US-9914745-B2 Morpholino-based antisense agent INDIAN ASSOCIATION FOR THE CULTIVATION OF SCIENCE (IN) 2018-03-13 US disclosed