Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642073 | 1.00 | CTSK (0.47) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL1643165 | 1.00 | CTSK (0.47) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL4714038 | 0.93 | CTSK (0.46) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL21715590 | 0.93 | CTSK (0.46) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL17846215 | 0.93 | CTSK (0.46) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL17846169 | 0.92 | CTSK (0.45) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL391356 | 0.88 | P2RY2 (0.42) | ALDH1A1PKMHPGDMAPT | |
| SCHEMBL22690610 | 0.88 | CTSS (0.42) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL22690612 | 0.88 | CTSS (0.42) | CTSKCTSSALDH1A1LMNAPKM | |
| SCHEMBL389645 | 0.88 | P2RY2 (0.42) | ALDH1A1PKMHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914740-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-13 | — | — | US | disclosed |