Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180466 | 0.75 | KDM4E (0.38) | KDM4EHTTALDH1A1F2GAA | |
| SCHEMBL12301085 | 0.74 | KDM4E (0.36) | KDM4EHTTALDH1A1POLBF2 | |
| SCHEMBL17193802 | 0.73 | KDM4E (0.34) | KDM4EHTTALDH1A1LMNAF2 | |
| SCHEMBL12233255 | 0.73 | KDM4E (0.35) | KDM4EHTTALDH1A1LMNAF2 | |
| SCHEMBL12301086 | 0.71 | KDM4E (0.33) | KDM4EHTTALDH1A1POLBF2 | |
| SCHEMBL14449367 | 0.70 | KDM4E (0.33) | KDM4EHTTALDH1A1F2GAA | |
| SCHEMBL25513496 | 0.70 | HTR1A (0.37) | AKT1KDM4EHTTALDH1A1F2 | |
| SCHEMBL18469509 | 0.70 | KDM4E (0.33) | KDM4EHTTALDH1A1F2GAA | |
| SCHEMBL25513578 | 0.69 | IRAK4 (0.36) | AKT1KDM4EHTTALDH1A1F2 | |
| SCHEMBL19954256 | 0.68 | SLC6A2 (0.35) | AKT1KDM4EHTTALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |