SCHEMBL19954744

SCHEMBL19954744

CCC(N)(CC(C)N)C(CC)(CC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.37
TAAR1 Q96RJ0 3/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
KIF11 P52732 2/20 0.36
KCNN4 O15554 1/20 0.34
MAOB P27338 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
GRIN1 Q05586 3/20 0.33
GRIN2A Q12879 3/20 0.33
GRIN2D O15399 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19954763 0.83 KCNN4 (0.44) TAAR1SLC6A2CYP1A2CYP2D6KIF11
SCHEMBL19954798 0.74 KIF11 (0.39) TAAR1SIGMAR1CYP1A2CYP2D6KIF11
SCHEMBL1538286 0.74 KCNN4 (0.39) TAAR1CYP1A2CYP2D6KIF11KCNN4
SCHEMBL1059898 0.72 KCNN4 (0.48) TAAR1KCNN4MAPK1
SCHEMBL19954716 0.71 TAAR1 (0.46) TAAR1SLC6A2CYP1A2CYP2D6KIF11
SCHEMBL19954762 0.70 TAAR1 (0.38) TAAR1SLC6A2CYP1A2CYP2D6KIF11
SCHEMBL1221602 0.70 MAOA (0.45) MAOATAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL10831632 0.70 TAAR1 (0.56) MAOATAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL28366818 0.69 KCNN4 (0.46) TAAR1SLC6A2CYP1A2CYP2D6KIF11
SCHEMBL17336291 0.68 CYP2D6 (0.41) MAOATAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917273-B2 Cross-linking polymer and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-13 US disclosed