Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282186 | 0.89 | LMNA (0.64) | LMNATSHRALDH1A1ESR1TDP1 | |
| SCHEMBL684816 | 0.87 | RAB9A (0.50) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL18522327 | 0.85 | MAPT (0.50) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL14607661 | 0.84 | CYP1A2 (0.48) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL20776970 | 0.84 | TSHR (0.45) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL26413289 | 0.83 | MAPT (0.49) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL20936355 | 0.83 | CA12 (0.50) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL13681405 | 0.81 | RAB9A (0.42) | MAPTLMNATSHRALDH1A1ESR1 | |
| SCHEMBL14143932 | 0.81 | TSHR (0.59) | TSHRMAPK1HTT | |
| SCHEMBL12126258 | 0.79 | MAPT (0.49) | MAPTLMNATSHRALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914816-B2 | Methods and materials for depolymerizing polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |