Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136350 | 0.89 | NPSR1 (0.44) | DRD2DRD4MAPK1KDM4EHIF1A | |
| SCHEMBL21985476 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL861408 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL8151767 | 0.84 | PAOX (0.55) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL3251521 | 0.82 | MAPK1 (0.52) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL8761519 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL13453975 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL19955013 | 0.79 | MAPK1 (0.44) | SMN1; SMN2TP53MAPK1KDM4EHIF1A | |
| SCHEMBL5956993 | 0.79 | USP2 (0.58) | SMN1; SMN2TP53DRD2DRD4MAPK1 | |
| SCHEMBL18211581 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53DRD2DRD4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914747-B2 | Extended betulinic acid analogs | VIIV Healthcare UK (No.5) Limited (GB) | 2018-03-13 | — | — | US | disclosed |