Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076614 | 0.74 | PLA2G1B (0.37) | PLA2G1BPLA2G2A | |
| SCHEMBL17515587 | 0.73 | CHRM2 (0.32) | — | |
| SCHEMBL19255420 | 0.70 | PLA2G1B (0.35) | PLA2G1BPLA2G2A | |
| SCHEMBL18737149 | 0.70 | PLA2G1B (0.39) | PLA2G1BPLA2G2A | |
| SCHEMBL24926234 | 0.70 | PLA2G1B (0.35) | PLA2G1BPLA2G2A | |
| SCHEMBL20803799 | 0.69 | PLA2G1B (0.36) | PLA2G1BPLA2G2A | |
| SCHEMBL25006027 | 0.69 | DNM1 (0.32) | — | |
| SCHEMBL18844660 | 0.69 | DNM1 (0.42) | — | |
| SCHEMBL25101380 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL18848365 | 0.68 | DNM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914755-B2 | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized | ALLERGAN, INC. (US) | 2018-03-13 | — | — | US | disclosed |