SCHEMBL1995534

SCHEMBL1995534

CSCC[C@@H](NC(=O)c1ccccc1)C(=O)NO

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.69
ALDH1A1 P00352 1/20 0.69
CRHBP P24387 1/20 0.69
KMT2A Q03164 1/20 0.69
CRHR2 Q13324 1/20 0.69
ANPEP P15144 1/20 0.64
NPC1 O15118 1/20 0.55
CA2 P00918 2/20 0.54
CA1 P00915 1/20 0.54
CTSB P07858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.52
LMNA P02545 1/20 0.52
TSHR P16473 1/20 0.52
CCR1 P32246 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997609 1.00 MEN1 (0.69) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL9461939 0.87 CA2 (0.69) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL1158031 0.87 CA2 (0.69) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL1158033 0.87 CA2 (0.69) MEN1ALDH1A1CRHBPKMT2ACRHR2
Water SCHEMBL28867161 0.85 CA2 (0.67) MEN1ALDH1A1CRHBPKMT2ACRHR2
Lithium SCHEMBL6646645 0.85 CA2 (0.67) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL6646636 0.85 CA2 (0.67) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL2692997 0.84 ALDH1A1 (0.53) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL203318 0.84 ALDH1A1 (0.53) MEN1ALDH1A1CRHBPKMT2ACRHR2
SCHEMBL4388416 0.84 MEN1 (0.63) MEN1ALDH1A1CRHBPKMT2ACRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2338878-A2 N-hydroxyamide derivatives possessing antibacterial activity Vicuron Pharmaceuticals, Inc. (US) 2011-06-29 EP disclosed