Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18107268 | 1.00 | LMNA (0.50) | LMNAOPRM1ALDH1A1TDP1LCK | |
| SCHEMBL28605961 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL28357777 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL27901401 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL18107230 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL28539807 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL28357779 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL18107409 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL17766889 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD | |
| SCHEMBL16737284 | 0.97 | LMNA (0.54) | LMNAOPRM1ALDH1A1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709280-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2014-04-29 | — | — | US | disclosed |
| US-8696933-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | VANDERBILT UNIVERSITY | 2012-10-04 | — | — | US | disclosed |
| CN-102695741-A | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS LLC | 2012-09-26 | — | — | CN | disclosed |
| US-20120205582-A1 | POLAR NEMATIC COMPOUNDS | VANDERBILT UNIVERSITY | 2012-08-16 | — | — | US | disclosed |
| US-8168084-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110147655-A1 | POLAR NEMATIC COMPOUNDS | NATIONAL SCIENCE FOUNDATION | 2011-06-23 | — | — | US | disclosed |
| US-3933837-A | 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters | STERLING DRUG INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205582-A1 | POLAR NEMATIC COMPOUNDS | BCOR, LATS1, LATS2 | LMNA 2172/4885OPRM1 2491/4885ALDH1A1 4664/4885 |
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | LATS2, CCNH, CRY1 | LMNA 2035/4885OPRM1 3511/4885ALDH1A1 4318/4885 |
| US-20110147655-A1 | POLAR NEMATIC COMPOUNDS | BCOR, LATS1, LATS2 | LMNA 2172/4885OPRM1 2491/4885ALDH1A1 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.