Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389771 | 0.82 | LMNA (0.46) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL23977846 | 0.78 | LMNA (0.44) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL2700038 | 0.78 | LMNA (0.44) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL26832966 | 0.78 | LMNA (0.44) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL10339422 | 0.78 | LMNA (0.58) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL10339865 | 0.78 | LMNA (0.58) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9807042 | 0.78 | LMNA (0.58) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9807044 | 0.78 | LMNA (0.58) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL3389065 | 0.77 | LMNA (0.41) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL11567681 | 0.77 | LMNA (0.41) | LMNAPOLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293216-A1 | POLYMERS FORMED FROM METHYLENE BETA-KETOESTER MONOMERS AND PRODUCTS FORMED THEREFROM | Sirrus, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |