Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19955514 | 0.90 | NR1I2 (0.38) | NR1I2MAPTTHRB | |
| SCHEMBL19955789 | 0.90 | NR1I2 (0.37) | NR1I2MAPTTHRB | |
| SCHEMBL19955591 | 0.89 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL19955676 | 0.88 | NR1I2 (0.37) | NR1I2MAPTMEN1ALDH1A1GAA | |
| SCHEMBL18929725 | 0.87 | NR1I2 (0.36) | NR1I2MAPTTHRB | |
| SCHEMBL19955743 | 0.84 | NR1I2 (0.36) | NR1I2MAPTTHRBMEN1ALDH1A1 | |
| SCHEMBL19955627 | 0.84 | NR1I2 (0.35) | NR1I2 | |
| SCHEMBL19955744 | 0.83 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL18944148 | 0.82 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL19955611 | 0.82 | NR1I2 (0.41) | NR1I2MAPTTHRBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166925-B1 | ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION | VIIV HEALTHCARE UK LTD (GB) | 2018-03-14 | — | — | EP | disclosed |