Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26451093 | 0.85 | PDE4D (0.39) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL23534115 | 0.81 | CDK2 (0.43) | HRH4 | |
| SCHEMBL1983193 | 0.75 | CHUK (0.46) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL1983195 | 0.75 | CHUK (0.46) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL1982045 | 0.75 | CHUK (0.46) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL1982047 | 0.75 | CHUK (0.46) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL14234873 | 0.74 | NUDT1 (0.45) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL1984140 | 0.73 | TLR8 (0.41) | TLR8 | |
| SCHEMBL1984139 | 0.73 | TLR8 (0.41) | TLR8 | |
| SCHEMBL9287279 | 0.73 | TLR8 (0.53) | TLR8TLR7HRH4CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2899193-B1 | Crystalline form of abacavir that is essentially free of solvent | ESTEVE QUÍMICA S A (ES) | 2018-03-14 | — | — | EP | disclosed |