SCHEMBL19956008

SCHEMBL19956008

Bc1c(O)c(O)c(O)c(C)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.41
PDE4A P27815 3/20 0.41
PDE4C Q08493 3/20 0.41
PDE4D Q08499 3/20 0.41
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
SENP1 Q9P0U3 1/20 0.38
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
HNF4A P41235 1/20 0.36
AR P10275 3/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447299 0.83 SENP1 (0.54) PDE4BPDE4APDE4CPDE4DHDAC4
Phenol SCHEMBL28264841 0.78 SENP1 (0.59) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL27577881 0.77 SENP1 (0.46) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL28248289 0.77 SENP1 (0.58) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL18466722 0.77 PDE4B (0.45) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL32679359 0.76 PDE4B (0.48) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL19956058 0.76 PDE4B (0.54) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL27608966 0.74 SENP1 (0.54) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL19956864 0.74 PDE4B (0.52) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL19956060 0.74 MAPT (0.39) PDE4BPDE4APDE4CPDE4DSENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3127988-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2018-03-14 EP disclosed